Peculiarities of changes in hormonal and biochemical parameters in patients with pcos and autoimmune thyroid disease
DOI:
https://doi.org/10.21856/j-PEP.2018.1.01Keywords:
polycystic ovary syndrome, autoimmune thyroid disease, subclinical hypothyroidismAbstract
It was examined 55 patients with PCOS that were divided into groups depending on the functional state of the thyroid gland: 21 women with autoimmune thyroiditis in euthyroid stage, 14 women with autoimmune thyroiditis which was combined with subclinical hypothyroidism, 20 — without a thyroid dysfunction. It was found that the euthyroid dysfunction aggravates the typical for the classic phenotype of PCOS the hormonal disorders — increase the total testosterone, the free androgen index and decrease the sex-steroid-binding globulin. The absence of a correlation between TTG and LH, LG / FSH indicates different mechanisms formation of PCOS and thyroid pathology.
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