GENDER FEATURES OF MANIFESTATION AND CLINICAL COURSE OF PROLACTINOMA

Authors

  • Gogitidze T. G. SI «V. Danilevsky Institute for Endocrine Pathology Problems of the NAMS of Ukraine», Kharkiv

DOI:

https://doi.org/10.21856/j-PEP.2013.3.07

Keywords:

prolactinoma, prolactin, hypophysis adenoma.

Abstract

It was studied 40 patients (6 men and 34 women) with prolactinoma. It was conducted a quan-
titative and qualitative analysis of complaints at the time of disease manifestation and examination.
The main specific clinical manifestations of pathological hyperprolactinemia in women and men have
impaired of sexual function. Severity of complaints of a general nature for men concealed clinical
symptoms of hyperprolactinemia and complicates timely diagnosis of prolactinoma. The frequency of
neurological and neuro-ophthalmic complaints in patients with prolactinoma depends on the size of
the hypophysis adenoma. In 15 % of patients prolactinomas characterized by a long asymptomatic
and are diagnosed at a stage invasive macroadenomas.

References

Verhelst J, Abs R. Treat Endocrinol 2003; 2(1):23-32.

Marova EI. Nejrojendokrinologija, Jaroslavl’ , 1999:506 p.

Beckers A, Adam C, Ciccarelli A, et al. ENEA abstr. Congress, Sorrento, 2004:23.

Kravchun NA. 100 izbrannyh lekcij po jendokrinologii, Har’kov, 2009: 842-847.

Ciccarelli A, Daly AF, Beckers A. Pituitary 2005; 8(1):3-6.

Korneeva IE. Klinika, diagnostika i lechenie besplodija u zhen-shhin s funkcional’noj giperprolaktinemiej, Moskva , 2003:20 p.

Horseman ND. Prolactin, Boston , 2001:184 p.

Dedov II, Mel’nichenko GA, Romancova TI. Sindrom giperprolaktinemii, Moskva , 2004:98 p.

Mel’nichenko GA, Marova EI, Dzeranova LK. Diagnostika i lechenie nejrojendokrinnyh zabolevanij, Moskva , 2003:256 p.

Vance ML, Thorner MO. Hyperprolactinemic syndromes and management, Philadelphia , 1989:408-418.

Melmed S, Casanueva F, Andrew R, et al. J Clin Endocrinol Metabol 2011; 96(2):273–288.

Klimov AN, Nikul’cheva JuG. Obmen lipidov i lipoproteidov i ih narushenija, Sankt-Peterburg , 1999:505 p.

Kars M, et al. Netheland J Med 2010; 68(3):104-112.

Colao A, Lombardi G. Lancet 1998; 352:1455-1461.

Levy MJ, Matharu M, Goadsby P. Curr Pain Headache Rep 2008; 12(1):74-78. Tejlor RB. Trudnyj diagnoz, Moskva , 1995; 1:400-418.

Dzhanashija PH, Nazarenko VA, Nikolenko SA. Dislipidemii: klinika, diagnostika, lechenie, Moskva , 2000: 48 p.

Tejlor RB. Trudnyj diagnoz, Moskva , 1995; 1:400-418.

Beaumont J, Carlson L, Cooper RG, et al. Bull WHO 1970; 43:891.

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Published

2013-10-10

How to Cite

Gogitidze, T. G. (2013). GENDER FEATURES OF MANIFESTATION AND CLINICAL COURSE OF PROLACTINOMA. Problems of Endocrine Pathology, 45(3), 57-62. https://doi.org/10.21856/j-PEP.2013.3.07

Issue

Section

CLINICAL ENDOCRINOLOGY