Pathogenetic mechanisms and therapeutic aspects of OMEGA-3 polyunsaturated fatty acids in diabetes mellitus (literature review and own data)
DOI:
https://doi.org/10.21856/j-PEP.2018.4.06Keywords:
omega-3 polyunsaturated fatty acids, mechanism of action, diabetes mellitusAbstract
In the review the present day data and own results about mechanisms of omega-3 polyunsaturated fatty acids are presented. The peculiarities of influence on 1) glucose metabolism; 2) chronic inflammatory process; 3) platelet aggregation and hemostasis; 4) endothelial dysfunction; 5) blood pressure regulation; 6) parameters of the vascular wall rigidity; 7) heart rate variability; 8) development of arrhythmias are presented. Results of our study prove that its prescription is accompanied by hypolipidaemic effect. Numerous studies report salutary effects of omega-3 polyunsaturated fatty acids on cardiovascular diseases risk factors and justify the benefits of using this drug by diabetes mellitus.
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