TY - JOUR AU - Sergiyenko, V. A. AU - Segin, V. B. AU - Azhmi, Samir AU - Sergiyenko, A. A. PY - 2013/10/10 Y2 - 2024/03/28 TI - ARTERIAL WALL STIFFNESS, INSULIN RESISTANCE, BRAIN NATRIURETIC PEPTIDE AND THE FUNCTIONAL AND STRUCTURAL CHANGES OF THE MYOCARDIUM AT DIABETIC CARDIOVASCULAR AUTONOMIC NEUROPATHY JF - Problems of Endocrine Pathology JA - PEP VL - 45 IS - 3 SE - DO - 10.21856/j-PEP.2013.3.06 UR - https://www.jpep.endocrinology.org.ua/index.php/1/article/view/513 SP - 22-29 AB - <p>It was studied 65 patients with type 2 diabetes: 12 patients without cardiovascular disease, 14 —<br>with subclinical, 18 — with functional, 21 — with functional-organic stage of diabetic cardiovascular<br>autonomic neuropathy. Type 2 diabetes without a cardiovascular disease is characterized by a<br>tendency to increase the arterial wall stiffness. The subclinical stage of diabetic autonomic neuropathy<br>is characterized by increased pulse wave velocity in the aorta (PWVao). The functional stage<br>characterized by an increase of the index of augmentation in aortic and brachial arteries, PWVao,<br>ambulatory arterial stiffness index. Functional- organic stage is characterized by pathological changes<br>of the arterial wall striffnesss. The diabetic cardiovascular autonomic neuropathy is accompanied by<br>increased of insulin resistance, insulin, HOMA-IR, NT-proBNP. There is a direct correlation between<br>NT-proBNP, left ventricular mass and PWVao</p> ER -