@article{Somova_Gladkova_Karpenko_Koreneva_Chistyakova_Selyukova_2010, title={PHYTOESTROGENS EFFECT ON SEXUAL HORMONES LEVEL AND FERTILITY OF RATS }, volume={31}, url={https://www.jpep.endocrinology.org.ua/index.php/1/article/view/914}, DOI={10.21856/j-PEP.2010.1.13}, abstractNote={<p>The influence of 30-day application of phytoestrogens compound to postpubertal male and female rats on the level of sexual hormones, gametes maturation and fertilization capacity was experimentally studied. Long-term phytoestrogenes supplies into animal’s organism bring out substantial changes in the level of sexual hormones. In females different estradiol contents are levelled at the estrus-diestrus stages that is typical for intact females. In males there was a considerable increase of estradiol, in a lesser degree — testosterone. Hence, the testosterone-esrtadiol ratio is altered. Morphological structural changes in male and female gametes, decreased spermatozoa motility, impaired embryonic implantation, a high rate of embryonic mortality are observed.</p>}, number={1}, journal={Problems of Endocrine Pathology}, author={Somova, E. V. and Gladkova, A. I. and Karpenko, N. A. and Koreneva, Yevheniia and Chistyakova, Elina and Selyukova, Nataliia}, year={2010}, month={Mar.}, pages={86-93} }