@article{Сергiєнко_Селюкова_Черевко_Бондаренко_Перець_Толмачова_2021, title={WEIGHT INDICATORS AND HISTOLOGICAL STRUCTURE OF RAT FEMUR OFFSPRING OF STRESSED MOTHERS AT GESTATIONAL CHANGES OF ESTROGEN AND LEPTIN SYSTEM LEVELS}, volume={52}, url={https://www.jpep.endocrinology.org.ua/index.php/1/article/view/496}, DOI={10.21856/j-PEP.2015.2.14}, abstractNote={<p>It was established antenatal origin and pathogenetic affinity of obesity and osteopathies. It was reviewed leptin’s participation at the development of these pathologies. It was shown that high levels of leptin which inherent of gestational stressed mothers’ offspring activates hondro- and osteogenesis, increasing the reparative effects of estrogen in the locomotor’ system tissues. Moreover the excessive increase of systemic leptin’s level is a cause of pathological changes in cartilage and bone tissues which leads to the formation of osteophytes and sclerosis.</p>}, number={2}, journal={Problems of Endocrine Pathology}, author={Сергiєнко Л.Ю. and Селюкова, Н.Ю. and Черевко, Г. М. and Бондаренко, Т. В. and Перець, О. В. and Толмачова, Л. М.}, year={2021}, month={Aug.}, pages={101-109} }