VITAMIN D STATUS IN OUTPATIENTS ATTENDING THE CENTER OF ENDOCRINOLOGY
Keywords:vitamin D status, predictors of the development of vitamin D deficiency
Background. Deficiency of vitamin D are common among the Ukrainian population. However, the results of the status of vitamin D in the population of Ukraine are limited. The aim of the study – to evaluate the vitamin D levels in persons attending outpatient department of the center of endocrinology. Materials and methods. A cross-sectional study was conducted in outpatients who visited the endocrinology center. After obtaining informed consent, we collected information about the examined adults and conducted a blood sampling to determine 25(OH)D level using the electrochemiluminescence method on the fully automated cobas elecys E411 system. Vitamin D content was compared in different groups using the Mann-Whitney or Kruskal-Wallis tests and a multiple linear regression analysis was conducted to detect promoters that affect vitamin D levels. Results. Under the supervision of 810 patients, it was found that the incidence of vitamin D deficiency (<20 ng/ml) was observed in 569 (70.2% 95% CI: 63.4–73.8) and insufficiency (20–29.9 ng/ml) was observed in 189 (23.3%) persons. In the univariate analysis, vitamin D levels were statistically significantly lower in the younger age group and in excessive body weight. After multiple linear regression analysis the place of residence in the radiation-polluted area, the presence of type 2 diabetes mellitus were identified as statistically significant predictors of the development of vitamin D deficiency. Conclusion. We have identified a high incidence of vitamin D insufficiency and deficiency in patients attending the endocrinology center. After multiple linear regression analysis the place of residence in the radiation-polluted area, the presence of type 2 diabetes mellitus were identified as statistically significant predictors of the development of vitamin D deficiency. Therefore, such people should be examined for the content of vitamin D in serum.
Keywords: vitamin D status, predictors of the development of vitamin D deficiency
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