ABOUT THE METABOLIC DISODERS IN PATIENTS WITH SLOWLY PROGRESSING AUTOIMMUNE DIABETES OF ADULTS

Authors

  • Tikhonova T. M. SI "V. Danilevsky Institute for Endocrine Pathology Problems of the NAMS of Ukraine", Kharkiv

DOI:

https://doi.org/10.21856/j-PEP.2012.1.02

Keywords:

slowly progressing autoimmune diabetes of adults, type 1 and type 2 diabetes mellitus, lipid metabolism, carbohydrate metabolism, metabolic disorders

Abstract

A comparative analysis of indicators of carbohydrate and lipid metabolism in patients with slowly progressing autoimmune diabetes of adults (LADA) with those in patients with type 1 and type 2 diabetes mellitus identified certain features. Thus, a blood glucose level in the diagnosis of disease in LADA patients was significantly higher than in the patients with type2 diabetes. In patients with established LADA the oral hypoglycemic therapy was ineffective, which determines whether the timely insulin appointment to these patients. Against the background of insulin therapy in LADA patients revealed more stable indicators of glycemic control than those determined in patients with type 1 diabetes. Patients are set LADA expressed disturbances of lipid metabolism similar to those in patients with type 2 diabetes. The presence of a specific subset in LADA patients anthropometric markers of the metabolic syndrome is accompanied by increased dislipoproteidemia, namely an increase in the coefficient of atherogenicity and decrease blood levels of high density lipoprotein cholesterol.

References

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Published

2012-03-15

How to Cite

Tikhonova, T. M. (2012). ABOUT THE METABOLIC DISODERS IN PATIENTS WITH SLOWLY PROGRESSING AUTOIMMUNE DIABETES OF ADULTS . Problems of Endocrine Pathology, 39(1), 16-25. https://doi.org/10.21856/j-PEP.2012.1.02

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Section

CLINICAL ENDOCRINOLOGY