PROGNOSTIC VALUE OF PAPP-A LEVEL IN PROGRESSING OF UNSTABLE STENOCARDIA IN PATIENTS WITH ACCOMPANYING TYPE 2 DIABETES
DOI:
https://doi.org/10.21856/j-PEP.2013.2.03Keywords:
unstable stenocardia, type 2 diabetes, PAPP-A, HOMAAbstract
It is proved in work that in patients with unstable stenocardia and type 2 diabetes is observed
increase of level of PPAP-A on 31,4 % in comparison with patients without diabetes. It is shown that
PAPP-A level positively correlates with levels of glycosylated hemoglobin and insulin, and also with
the HOMA index that is connected with development and progressing of insulin resistance in patients
with unstable stenocardia and type 2 diabetes. The connects of PAPP-A in blood plasma > 6 MU/l is
an important factor of increase in risk of adverse prognosis of progressing unstable stenocardia with
accompanying type 2 diabetes.
References
Bilovol OM, Kravchun PG. Osnovy diagnostyky, likuvannya ta profilaktyky osnovnyh kardiologichnyh zahvoryuvan’, Kharkiv, 2009;
:402 p..
Kravchun PG, Shelest OM. Nestabil’na stenokardiya: klinika, diagnostyka, dyferentsijne likuvannya, Kharkiv, 2006; 1:267 p..
Shevchenko OP, Slesareva YuS, Shevchenko AO. Ros kardiol zhurn 2008; 6:45–50.
Consuegra-Sanchez L, Fredericks S, Kaski JC. Atherosclerosis 2008; 12:634–638.
Khosravi J, Diamandi A, Krishna RG, et al. Clin Biochem 2011; 35:531–538.
Ford ES, Giles WH. Diabetes Care 2003; 26(3):575–581.
Bayes-Genis A, Conover CA, Overgaard MT, et al. New Engl J Med 2001; 345:1022–1029.
Valcnsisc H, Liu VY, Fcderici M, et al. Diabetotogia 2006; 39:952-960.
Li X, Liu Q, Zhou T, et al. Med Hypotheses 2008; 70(3):597–599.
Haffner SM, D’Agostino RJ, Mykkanen L, et al. Diabetes Care 2009; 22:562-568.
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