Ultrastructure of Sertoli and Leydig cells in the rat testis after use of tribestan on the background of vasoconstrictor exposure

Authors

  • Brechka N. M. SI «V. Danilevsky Institute of Endocrine Pathology Problems of NAMS of Ukraine», Kharkiv, Ukraine

DOI:

https://doi.org/10.21856/j-PEP.2014.2.10

Keywords:

Sertoli cells, Leydig cells, ultrastructure, mitochondrial dysfunction, serotonin hydrochloride, Tribestan

Abstract

t was presented the experimental data about ultrastructural organization of Sertoli cells and Leydig cells of the testes of rats exposed to the toxic effects of serotonin hydrochloride, which causes mitochondrial dysfunction and activates catabolic intracellular processes; the depth and severity of these organelles violations exist within the physiological compensation and are reversible. It was found development of significant positive reparation of the cells ultrastructure of the rats testes treated with herbal medicines Tribestan on the background damaging effect on serotonin hydrochloride. In Sertoli cells decreases the degree of the cytoplasm and nucleus edema; destruction of mitochondria and other membrane structures are absent. It was increased the number of ribosomes and polysomes in the cytoplasm. At Tribestan administration on the background damaging effect of serotonin hydrochloride the ultrastructure of Leydig cells were reparated.

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Published

2014-05-22

How to Cite

Brechka, N. M. (2014). Ultrastructure of Sertoli and Leydig cells in the rat testis after use of tribestan on the background of vasoconstrictor exposure. Problems of Endocrine Pathology, 48(2), 65-70. https://doi.org/10.21856/j-PEP.2014.2.10

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