CICULATORY LEVELS OF RETINOL-BINDING PROTEIN 4 IN PATIENTS WITH TYPE 2 DIABETES, COMPLICATED BY NON-ALCOHOLIC FATTY LIVER DISEASE

Authors

  • Tyzhnenko T. V. SI «V. Danilevsky Institute of Endocrine Pathology Problems of NAMS of Ukraine», Kharkiv, Ukraine
  • Karachentsev Y. I. SI «V. Danilevsky Institute of Endocrine Pathology Problems of NAMS of Ukraine», Kharkiv, Ukraine; Kharkiv Postgraduate Medical Academy
  • Kravchun N. A. SI «V. Danilevsky Institute of Endocrine Pathology Problems of NAMS of Ukraine», Kharkiv, Ukraine
  • Poltorak V. V. SI «V. Danilevsky Institute of Endocrine Pathology Problems of NAMS of Ukraine», Kharkiv, Ukraine
  • Gorshunska M. Y. Kharkiv Postgraduate Medical Academy
  • Jаnsen E. National Institute for Public Health and the Environment, Bilthoven, The Netherlands
  • Krasova N. S. SI «V. Danilevsky Institute of Endocrine Pathology Problems of NAMS of Ukraine», Kharkiv, Ukraine
  • Leshchenko Zh. A. SI «V. Danilevsky Institute of Endocrine Pathology Problems of NAMS of Ukraine», Kharkiv, Ukraine
  • Gladkih A. I. SI «V. Danilevsky Institute of Endocrine Pathology Problems of NAMS of Ukraine», Kharkiv, Ukraine
  • Chernyavskaya I. V. SI «V. Danilevsky Institute of Endocrine Pathology Problems of NAMS of Ukraine», Kharkiv, Ukraine
  • Cherniaieva A. A. SI «V. Danilevsky Institute of Endocrine Pathology Problems of NAMS of Ukraine», Kharkiv, Ukraine
  • Opaleiko Y. A. SI «V. Danilevsky Institute of Endocrine Pathology Problems of NAMS of Ukraine», Kharkiv, Ukraine
  • Pochernyayev A. K. SI «V. Danilevsky Institute of Endocrine Pathology Problems of NAMS of Ukraine», Kharkiv, Ukraine
  • Zavadska N. V. SI «V. Danilevsky Institute of Endocrine Pathology Problems of NAMS of Ukraine», Kharkiv, Ukraine

DOI:

https://doi.org/10.21856/j-PEP.2014.2.01

Keywords:

type 2 diabetes, non-alcoholic fatty liver disease, insulin resistance, retinolbinding protein 4

Abstract

It was determined levels of retinol-binding protein 4 (RBP4) in the blood of patients with type 2 diabetes mellitus with non-alcoholic fatty liver disease or its absence. In patients with type 2 diabetes was verified a significant increase of circulating levels of RBP4, the severity of which was significantly higher in non-alcoholic fatty liver disease, as well as their direct correlation with the presence of complications. The data obtained justify the use of indicators of circulatory levels of RBP4 as a new marker of the risk of non-alcoholic fatty liver disease in patients with type 2 diabetes and the selection of anti-diabetic therapy.

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Published

2014-05-22

How to Cite

Tyzhnenko, T. V., Karachentsev, Y. I., Kravchun, N. A., Poltorak, V. V., Gorshunska, M. Y., Jаnsen E., Krasova, N. S., Leshchenko, Z. A., Gladkih, A. I., Chernyavskaya, I. V., Cherniaieva, A. A., Opaleiko, Y. A., Pochernyayev, A. K., & Zavadska, N. V. (2014). CICULATORY LEVELS OF RETINOL-BINDING PROTEIN 4 IN PATIENTS WITH TYPE 2 DIABETES, COMPLICATED BY NON-ALCOHOLIC FATTY LIVER DISEASE. Problems of Endocrine Pathology, 48(2), 7-14. https://doi.org/10.21856/j-PEP.2014.2.01

Issue

Section

CLINICAL ENDOCRINOLOGY

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