PROGNOSTIC AND DIAGNOSTIC VALUE APELIN DURING OSTEOARTRITIS IN PATIENTS WITH OBESITY
Keywords:obesity, deforming osteoarthritis, apelin.
The role of adipose tissue adipokine — the apelin — in patients with arthropathy deformans and with its combination with obesity has been studied. A direct correlation dependency between the apelin level and the body mass index, and between the apelin and insulin resistance has been shown. Statistically significant increase of that index in patients with arthropathy deformans associated with the normal body mass and the obesity has been proven. The combination of the obesity and the arthropathy deformans insulin resistance goes along with the statistically significant increase of the apelin level. Given these results, we can assume a certain role of apelin in the arthropathy deformans
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