SERUM LEVEL OF VCAM-1, ICAM-1, E-SELECTIN IN TYPE 2 DIABETES AND OBESETY
DOI:
https://doi.org/10.21856/j-PEP.2015.3.06Keywords:
VEGF, type 2 diabetes, obesity, endothelial dysfunctionAbstract
The study revealed an elevation of serum levels of VCAM-1, ICAM-1, E-selectin in obese and nonobese type 2 diabetes patients and obese subjects without diabetes. An elevation of serum levels of VCAM-1, ICAM-1, E-selectin is associated with hyperglycemia and dyslipidemia in non-obese type 2 diabetes patients. An increase of VCAM-1, ICAM-1, E-selectin is associated with body mass index, an markers of insulin resistance and lipid metabolism in obese type 2 diabetes patients and obese subjects without diabetes. Detect changes point to the development of endothelial dysfunction in patients with type 2 diabetes with different body weight and obese subjects without diabetes.
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