SERUM LEVEL OF VCAM-1, ICAM-1, E-SELECTIN IN TYPE 2 DIABETES AND OBESETY
DOI:
https://doi.org/10.21856/j-PEP.2015.3.06Keywords:
VEGF, type 2 diabetes, obesity, endothelial dysfunctionAbstract
The study revealed an elevation of serum levels of VCAM-1, ICAM-1, E-selectin in obese and nonobese type 2 diabetes patients and obese subjects without diabetes. An elevation of serum levels of VCAM-1, ICAM-1, E-selectin is associated with hyperglycemia and dyslipidemia in non-obese type 2 diabetes patients. An increase of VCAM-1, ICAM-1, E-selectin is associated with body mass index, an markers of insulin resistance and lipid metabolism in obese type 2 diabetes patients and obese subjects without diabetes. Detect changes point to the development of endothelial dysfunction in patients with type 2 diabetes with different body weight and obese subjects without diabetes.
References
Basha B, Samuel SM, Triggle CR, et al. Exp Diabetes Res 2012; 2012:481840.
Jansson PA. J Intern Med 2007; 262(2):173-183.
Uğurlu N, Gerceker S, Yülek F, et al. Intern Med 2013; 52(19):2173-2178.
Nakashima Y, Raines EW, Plump AS, et al. Arterioscler Thromb Vasc Biol 1998; 18:842-851.
Blankenberg S, Barbaux S, Tiret L. Atherosclerosis 2003; 170:191-203.
Binder FP, Ernst B. Chimia (Aarau) 2011; 65(4):210-213.
Empen K, Frost RJ, Geiss HC, et al. Cardiovasc Diabetol 2003; 2:17.
Mizia-Stec K, Gąsior Z, Zahorska-Markiewicz B, et al. Diabetologia Doświadczalna i Kliniczna 2003; 3(6):523-529.
Thorand B, Baumert J, Chambless L, et al. Arterioscler Thromb Vasc Biol 2006; 26(2):398-405.
Hadi AR, Suwaidi J. Vasc Health Risk Manag 2007; 3(6):853-876.
Ruszkowska-Ciastek B, Sokup A, Wernik T, et al. J Zhejiang Univ Sci B 2015; 16(5):355-361.
Liu JJ, Yeoh LY, Sum CF, et al. J Diabetes Complications 2015; 29(5):707-712.
Joy NG, Tate DB, Younk LM, Davis SN. Diabetes 2015; 18:141729.
Sozer V, Himmetoglu S, Korkmaz GG, et al. Minerva Med 2014; 105(3):237-244.
Mogensen CE, Christensen CK, Vittinghus E. Diabetes 1983; 32(2):64-78.
Tangvarasittichai S. World J Diabetes 2015; 6(3):456-480.
Bornfeldt KE, Tabas I. Cell Metab 2011; 14(5):575-585.
Pansuria M, Xi H, Li L, et al. Front Biosci (Schol Ed) 2012; 4:916-931.
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