THYROID HORMONE LEVELS IN OFFSPRING OF MOTHERS WHICH SMOKED DURING PREGNANCY AND HAD MALNUTRITION

Authors

  • Sokolova S. S. SI «V. Danilevsky Institute of Endocrine Pathology Problems of NAMS of Ukraine», Kharkiv, Ukraine; Kharkiv Postgraduate Medical Academy
  • Sregiyenko L. Yu. SI «V. Danilevsky Institute of Endocrine Pathology Problems of NAMS of Ukraine», Kharkiv, Ukraine
  • Yakovtsova I. I. Kharkiv Postgraduate Medical Academy
  • Bondarenko T. V. SI «V. Danilevsky Institute of Endocrine Pathology Problems of NAMS of Ukraine», Kharkiv, Ukraine

DOI:

https://doi.org/10.21856/j-PEP.2015.4.09

Keywords:

thyroid hormone levels, offspring, smoking pregnant, reduced maternal nutrition

Abstract

On the model of the combined effects of passive smoking and reducing of energy intake diet of pregnant female rats was shown that their offspring of both sexes in the postnatal life have disrupted age ensuring body’s thyroid hormone. At the same time a significant number of offspring at an early age have expressed hyperthyroidism at the background of lower body weight. It was expected that this impact is the cause of a high percentage the death of pups of mothers during the first months of life, as had been shown by the authors earlier. It was found that the stress functioning of thyroid system in female offspring of experimental mothers has changing influence on hypothyroid status and leads to obesity at young age.

References

Glioner D. Endocr Rev 1997; 18:404-433.

Lazarus JH. Treat Endocrinol 2005; 4:31-41.

Williams GR. J Neuroendocrinol 2008; 20:784-794.

Oliveira E. Moura EG, Santos-Silva AP, et al. J Endocrinol 2009; 202:397-405.

Soldin OP, Goughenour BE, Gilbert SZ, et al. Thyroid 2009; 19(8):817-823.

Barker DJ. J Amer Coll Nutr 2004; 23:588-595.

Wojtyła A. Gozdziewska M, Paprzycki P, Bilinski P. Ann Agricult Environmen Med 2012; 19(1):117-128.

Sokolova SS, et al. Probl Endokryn Patologii’ 2015;1:113-119.

Sergijenko LJu, et al. Probl Endokryn Patologii’ 2015; 2:110-118.

Sokolova SS, et al. Internauka. Nauchnaja diskussija: voprosy mediciny, 2015; 5-6(28):122-129.

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Published

2015-12-03

How to Cite

Sokolova, S. S., Sregiyenko, L. Y., Yakovtsova, I. I., & Bondarenko, T. V. (2015). THYROID HORMONE LEVELS IN OFFSPRING OF MOTHERS WHICH SMOKED DURING PREGNANCY AND HAD MALNUTRITION. Problems of Endocrine Pathology, 54(4), 71-78. https://doi.org/10.21856/j-PEP.2015.4.09