FEATURES OF IMMUNOINFLAMMATORY ACTIVATION AND ENDOTHELIAL FUNCTION IN PATIENTS WITH CORONARY HEART DISEASE ASSOCIATED WITH HYPOTHYROIDISM

Authors

  • Mykhailovska N. S. Zaporizhzhya State Medical University Department of General Practice — Family Medicine
  • Oleynik T. V. Zaporizhzhya State Medical University Department of General Practice — Family Medicine

DOI:

https://doi.org/10.21856/j-PEP.2015.4.05

Keywords:

ischemic heart disease, hypothyroidism, immunoinflammatory activation, endothelial dysfunction

Abstract

he presence of hypothyroidism in patients with coronary heart disease contributes to its progression. It was found that in patients with coronary heart disease associated with hypothyroidism, there is an increase markers of immunoinflammatory activation and endothelial dysfunction compared both to coronary heart disease patients without concomitant thyroid disease and patients with coronary artery disease with the structural changes of the thyroid gland in euthyroid state. Established the presence of correlations of neopterin levels, plasminogen activator inhibitor-1, endothelin-1 with hormones of the pituitary-thyroid level in patients with coronary heart disease with concomitant hypothyroidism.

References

Kravchenko VI, Postol SV. Mezhdunar Jendokrinol Zhurn 2011; 3(35):56-59.

Sawin CT, Castelli WT, Hershman JM, et al. Arch Intern Med 1985; 145:1386-1386.

Mitchenko OI, Romanov VJu, Logvynenko AO, et al. Zdorov’ja Ukrai’ny 2012; 20(297):27-29.

Galetta F, Franzoni F, Fallahi P, et al. Biomed Pharmacother 2010; 64(8):546-549.

Moskva HA, Lapovec’ LJe, Kihtjak OP. Visn Probl Biologii’ i Medycyny 2013; 2; 3(103):2011-2016.

Neves C, Alves M, Medina JL, Delgado JL. Rev Port Cardiol 2008; 27(10):1211-1236.

Volkova AR, Dora SV, Badmaeva MI, et al. Mezhdunar Jendokrinol Zhurn 2010; 3(27):24-26.

Fes’kova AA, Dobrysheva ES. Molodoj Uchenyj 2014; 17:207-210.

Rodionova TI, Samitin VV. Klinich Jeksperim Tireoidologija 2009; 5(1):26-29.

Marushko TV, Berezhnoj VV, Gavrilenko TI, Klubova AF. Ukr Revmatol Zhurn 2006; 23(1):33-36.

Cantürk Z, Cetinarslan B, Tarkun I, et al. Thyroid 2003; 13(10):971-977.

Erem C. Semin Thromb Hemost 2011; 37(1):17-26.

Kopica NP, Litvin EI, Petjunina OV, et al. Ukr Terapevt Zhurn 2006; 4:19-22.

Ruzhencova UJu. Lechashhij Vrach 2008; 1:87-92.

Nystrom T, Nygren A, Sjoholm A. Clin Science 2005; 12:121-128.

Degtjareva OV, Petjunina OV. Ukr Terapevt Zhurn 2008; 1:41-44.

Alessandris CD, Lauro R, Presta I, et al. Diabetologia 2007; 50(4):840-849.

Hueston WJ, King DE, Geesey ME. Clin Endocrinol (Oxf) 2005; 63:582-587.

Tuzcu A, Bahceci M, Gokalp D, et al. Endocr J 2005; 52:89-94.

Taddei S, Caraccio N, Virdis A, et al. J Clin Endocrinol Metab 2006; 91(12):5076-5082.

Jublanc C, Bruckert E, Giral P, et al. Atherosclerosis 2004; 172:7-11

Christ-Crain M, Meier C, Guglielmetti M, et al. Atherosclerosis 2003; 166:379-386.

Gursoy A, Ozduman Cin M, Kamel N, Gullu S. Int J Clin Pract 2006; 60(6):655-659.

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Published

2015-12-03

How to Cite

Mykhailovska, N. S., & Oleynik, T. V. (2015). FEATURES OF IMMUNOINFLAMMATORY ACTIVATION AND ENDOTHELIAL FUNCTION IN PATIENTS WITH CORONARY HEART DISEASE ASSOCIATED WITH HYPOTHYROIDISM. Problems of Endocrine Pathology, 54(4), 37-43. https://doi.org/10.21856/j-PEP.2015.4.05

Issue

Section

CLINICAL ENDOCRINOLOGY