Cytokine dysbalance in type 2 diabetes mellitus patients with prior myocardial infarction

Authors

  • Altunina N. V. A. Bohomolets Kyiv National Medical University, Kyiv

DOI:

https://doi.org/10.21856/j-PEP.2016.4.01

Keywords:

type 2 diabetes mellitus, postinfarction cardiosclerosis, cytokine dysbalance

Abstract

he article presents the results of the study of C-reactive protein, interleukin-6, tumor necrosis factor-α and interleukin-10 levels in postmyocardial infarction patients with type 2 diabetes mellitus. It was identified significantly higher concentrations of C-reactive protein, proinflammatory interleukin-6 and tumor necrosis factor-α and anti-inflammatory interleukin-10 in comparison with the control group. The study found that the combination of postinfarction cardiosclerosis and type 2 diabetes mellitus shows higher degree of activity of markers of systemic inflammation than in isolated course of disease, when identical anti-inflammatory protection. The data shows that the blood glucose levels directly affect the concentration of C-reactive protein and interleukin-10, whereas insulin resistance directly depends on the activity of inflammation markers.

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Published

2021-06-24

How to Cite

Altunina, N. V. (2021). Cytokine dysbalance in type 2 diabetes mellitus patients with prior myocardial infarction. Problems of Endocrine Pathology, 58(4), 7-13. https://doi.org/10.21856/j-PEP.2016.4.01

Issue

Section

CLINICAL ENDOCRINOLOGY