THE EFFECT OF FLAVONOIDS ON HORMONAL BACKGROUND CHANGES IN EXPERIMENTAL METABOLIC SYNDROME
DOI:
https://doi.org/10.21856/j-PEP.2016.2.09Keywords:
metabolic syndrome, quercetin, epigallocatechin gallate, sex steroids, cortisolAbstract
It was established the experimental metabolic syndrome development in males of Syrian Golden hamsters on the background of the hypercaloric diet for 5 weeks. Pathological changes of metabolic links manifested by insulin resistance, a decrease in the content of adiponectin, hypercortisolaemia, leptinresistance and imbalance of sex hormones. The administration of the investigated compounds — quercetin and epigallocatechin gallate largely correct these changes. Epigallocatechin gallate had more expressive effect than quercetin.
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