Adipokine`s profile effects on the metabolic disorders and cardiac remodeling in patients with arterial hypertension and type 2 diabetes
Keywords:hypertension, type 2 diabetes, visfatin, omentin, myocardial remodeling
The aim of the work was to study the effect of apelin and omentin`s activity on the progression of metabolic disorders and myocardial remodeling in patients with hypertension (AH) and type 2 diabetes (DM2). The study involved 44 patients with stage II and 2 degrees of AH, combined with DM2 type 2 and 42 patients with stage II and 2 degrees of hypertension without DM2. The control group consisted of 20 practically healthy persons. It has been found that during the combined course of AH and DM2 was observed hypervisfatinemiya and hypoomentinemiya that is significantly correlated with the development and progression of the atherogenic dyslipidemia, carbohydrate disorders, insulin resistance and myocardial remodeling, that greatly increases the cardiovascular risk in the patients.
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