Features of the lipid spectrum of blood in women with polycystic ovary syndrome

Authors

  • Arkhypkina T. L. SI «V. Danilevsky Institute of Endocrine Pathology Problems of NAMS of Ukraine», Kharkiv, Ukraine

DOI:

https://doi.org/10.21856/j-PEP.2017.3.01

Keywords:

polycystic ovary syndrome, dyslipidemia, overweight, insulin resistance, hyperandrogenia

Abstract

246 young women with PCOS were examined. It was found out that 81.4 % of patients had dyslipidemia, manifested by an increase in the levels of cholesterol, TG, LDL cholesterol, VLDL cholesterol, аtherogenic coefficient and decreased HDL cholesterol relative to healthy women. Insulin resistance, compensatory hyperinsulinaemia, hyperandrogenia and overweight aggravate lipid disorders and are independent factors in the formation of dyslipidemia in women with PCOS. The existing positive correlation between the TG/HDL cholesterol, cholesterol/HDL cholesterol, LDL cholesterol/HDL cholesterol and the HOMA-IR index allows us to use these ratios in patients with PCOS as an insulin resistance marker.

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Published

2021-06-24

How to Cite

Arkhypkina, T. L. (2021). Features of the lipid spectrum of blood in women with polycystic ovary syndrome. Problems of Endocrine Pathology, 61(3), 7-16. https://doi.org/10.21856/j-PEP.2017.3.01

Issue

Section

CLINICAL ENDOCRINOLOGY

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