Analysis of the interrelations for clusters of metabolic syndrome associated with impaired water-salt homeostasis, urolithiasis and other diseases of the urinary system
DOI:
https://doi.org/10.21856/j-PEP.2019.2.08Keywords:
urolithiasis, comorbid pathology, metabolic syndrome.Abstract
In order to assess the risks and interrelations of urolithiasis with comorbid pathology associated with metabolic syndrome, impaired water-salt homeostasis and other diseases of the urinary system there was conducted a retrospective epidemiological study of 443 patients with urolithiasis (40 of them — with relapses), as well as 203 healthy individuals on the basis of healthcare facilities in Ivano-Frankivsk region.
It is proved that the chances of urolithiasis are increasing with the presence of congenital malformations of the urinary system (OR = 3.18; 95 % CI = 1.54–6.56), chronic pyelonephritis (1.83; 1.15–2.94) and obesity (1.60; 1.11–2.29). The recurrences of kidney stone disease are associated, beside pyelonephritis (3.52; 1.80–6.89) and obesity (2.12; 1.02–4.40), with long-term immobilization after fractures (8.70; 1.10–68.70) and arterial hypertension (4.48; 1.01–3.85).
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