Analysis of the interrelations for clusters of metabolic syndrome associated with impaired water-salt homeostasis, urolithiasis and other diseases of the urinary system

Authors

  • Solomchak D. B. Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine
  • Kostitska I. O. Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine
  • Detsyk O. Z. Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine

DOI:

https://doi.org/10.21856/j-PEP.2019.2.08

Keywords:

urolithiasis, comorbid pathology, metabolic syndrome.

Abstract

In order to assess the risks and interrelations of urolithiasis with comorbid pathology associated with meta­bolic syndrome, impaired water-salt homeostasis and other diseases of the urinary system there was conducted a retrospective epidemiological study of 443 patients with urolithiasis (40 of them — with relapses), as well as 203 healthy individuals on the basis of healthcare facilities in Ivano-Frankivsk region.

It is proved that the chances of urolithiasis are increasing with the presence of congenital malformations of the urinary system (OR = 3.18; 95 % CI = 1.54–6.56), chronic pyelonephritis (1.83; 1.15–2.94) and obesity (1.60; 1.11–2.29). The recurrences of kidney stone disease are associated, beside pyelonephritis (3.52; 1.80–6.89) and obesity (2.12; 1.02–4.40), with long-term immobilization after fractures (8.70; 1.10–68.70) and arterial hyper­tension (4.48; 1.01–3.85).

References

Bojko AI, Gurzhenko AJu, Ganzhyj VV, Gubar’ AO. Klin Hirurgija 2013; 11: 51-53.

Spivacow FR, Del Valle EE, Lores E, Rey PG. Medicina (B Aires) 2016; 76 (6): 343-348.

Wong Y, Cook P, Roderick P, Somani BK. J Endourol 2016; 30 (3): 246-253. https://doi.org/10.1089/end.2015.0567.

Domingos F, Serra A. Scand J Urol 2014; 48 (5): 414-419. https://doi.org/10.3109/21681805.2014.903513.

Rendina D, De Filippo G, D’Elia L, Strazzullo P. J Nephrol 2014; 27 (4): 371-376. https://doi.org/10.1007/s40620-014-0085-9.

Dell’Orto VG, Belotti EA, Goeggel-Simonetti B, et al. Br J Clin Pharmacol 2014; 77 (6): 958-964. https://doi.org/10.1111/bcp.12283.

Wollin DA, Skolarikos A, Preminger GM. Curr Opin Urol 2017; 27 (5): 422-427. https://doi.org/10.1097/MOU.0000000000000427.

Carbone A, Al Salhi Y, Tasca A, et al. Minerva Urol Nefrol 2018; 70 (4): 393-400. https://doi.org/10.23736/S0393-2249.18.03113-2.

Roughley MJ, Belcher J, Mallen CD, Roddy E. Arthritis Res Ther 2015; 17 (1): 90. https://doi.org/10.1186/s13075-015-0610-9.

Cong X, Shen L, Gu X. Urolithiasis 2018; 46 (5): 453-457. https://doi.org/10.1007/s00240-018-1038-x.

Pradere B, Peyronnet B, Brochard C, et al. Prog Urol 2015; 25 (10): 557-564. https://doi.org/10.1016/j.purol.2015.05.001.

Zerwekh JE, Odvina CV, Wuermser LA, Pak CY. J Urol 2007; 177 (6): 2179-2184. https://doi.org/10.1016/j.juro.2007.01.156.

Mufti UB, Nalagatla SK. J Endourol 2010; 24 (10): 1557-1561. https://doi.org/10.1089/end.2010.0093.

Marien T, Miller NL. Urol Clin North Am 2015; 42 (4): 459-472. https://doi.org/10.1016/j.ucl.2015.05.009.

Kittanamongkolchai W, Mara KC, Mehta RA, et al. Clin J Am Soc Nephrol 2017; 12 (3): 476-482. https://doi.org/10.2215/CJN.06600616.

Forthofer RN, Lee ES, Hernandez M. Biostatistics: A Guide to Design, Analysis, and Discovery, Amsterdam, 2007: 502 p.

Downloads

Published

2021-06-30

How to Cite

Соломчак, Д. Б., Костіцька, І. О., & Децик, . О. З. (2021). Analysis of the interrelations for clusters of metabolic syndrome associated with impaired water-salt homeostasis, urolithiasis and other diseases of the urinary system. Problems of Endocrine Pathology, 68(2), 52-59. https://doi.org/10.21856/j-PEP.2019.2.08

Issue

Section

CLINICAL ENDOCRINOLOGY