EFFECT OF THE COMBINATION OF NONSTEROIDAL ANTI-INFL AMMATORY DRUG ON THE COURSE OF OSTEOARTHRITIS WITH CONCOMITANT HYPOTHYROIDISM

Authors

  • Nosivets D. S. SI «Dnepropetrovsk medical academy of the Ministry of Health of Ukraine», Dnipro. Ukraine

DOI:

https://doi.org/10.21856/j-PEP.2019.2.06

Keywords:

Обрані:pain syndrome, NSAIDs, osteoarthrosis, hypothyroidism, clinical efficacy

Abstract

Diseases of the thyroid gland are relevant to the current problem of modern society due to the wide, con­stant spread of this pathology and disorders associated with these diseases. Metabolic disorders negatively af­fect the state of bone and cartilage tissue, cause the development of a number of pathological conditions among which, of course, osteoarthritis is important. The effectiveness of the use of a fixed combination of paracetamol 500 mg and diclofenac sodium 50 mg tablets in the symptomatic treatment of patients with pain in osteoarthri­tis against the background of hypothyroidism has been studied. The study involved 348 patients aged from 18 to 92 years old who were shown a short-term course of anesthetic symptomatic therapy for pain in the presence of osteoarthritis in hypothyroidism. The course of treatment for each patient was selected individually and ranged from 1 to 7 days. Doses of the drug were determined individually, depending on the patient's age, the nature and course of the disease, tolerability and therapeutic efficacy of the fixed combination. A pronounced clinical efficacy of using the fixed combination in patients with pain syndrome in osteoarthritis on the background of hypothyroidism in a daily dose of 2 to 3 tablets for 3 to 7 days has been established. The obtained data on the clinical efficacy of the use of a fixed combination of paracetamol 500 mg and diclofenac sodium 50 mg tablets in the treatment of patients with pain in osteoarthritis against the background of hypothyroidism allow to recom­mend it for use in general clinical practice.

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Published

2019-06-13

How to Cite

Носівець, Д. С. . (2019). EFFECT OF THE COMBINATION OF NONSTEROIDAL ANTI-INFL AMMATORY DRUG ON THE COURSE OF OSTEOARTHRITIS WITH CONCOMITANT HYPOTHYROIDISM. Problems of Endocrine Pathology, 68(2), 40-45. https://doi.org/10.21856/j-PEP.2019.2.06

Issue

Section

CLINICAL ENDOCRINOLOGY