RELATIONSHIP BETWEEN CARBOHYDRATE EXCHANGE PARAMETERS AND INTERLEUKIN-22 IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION WITH REGARD TO CONCOMITANT TYPE 2 DIABETES MELLITUS

Authors

  • Zhuravleva M. I. Kharkiv National Medical University, Kharkiv, Ukraine
  • Ryndina N. G. Kharkiv National Medical University, Kharkiv, Ukraine
  • Dunaeva I. P. Kharkiv Postgraduate Medical Academy, Kharkiv, Ukraine

DOI:

https://doi.org/10.21856/j-PEP.2019.1.02

Keywords:

цукровий діабет, гострий інфаркт міокарду, інтерлейкін-22, інсулінорезистентність

Abstract

Worldwide, ischaemic heart disease is the single most common cause of death and its frequency is increasing. However, in Europe, there has been an overall trend for a reduction in ischaemic heart disease mortality over the past three decades [1]. Ischaemic heart disease now accounts for almost 1.8 million annual deaths, or 20 % of all deaths in Europe, although with large variations between countries [2, 3].Basu et al. found that althrought IL-22 was secreted by various types of cells, Th22 (CD4 + IL – 22 + T) cells were the critical source of IL-22 during the later stages of inflammation, indicating that Th22 may be essential for controlling chronic inflammation. The effector cytokine of Th22 cells is IL-22, which belongs to the IL-10 cytokine family and binds to the heterodimeric receptor complex consisting of the IL-10 receptor (IL-10R) β chain and IL-22R.

References

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Published

2021-07-06

How to Cite

Zhuravleva, M. I. ., Ryndina, N. G., & Dunaeva, I. P. . (2021). RELATIONSHIP BETWEEN CARBOHYDRATE EXCHANGE PARAMETERS AND INTERLEUKIN-22 IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION WITH REGARD TO CONCOMITANT TYPE 2 DIABETES MELLITUS. Problems of Endocrine Pathology, 67(1), 18-22. https://doi.org/10.21856/j-PEP.2019.1.02

Issue

Section

CLINICAL ENDOCRINOLOGY

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