PREVENTION AND COMPLEX TREATMENT OF INFLAMMATORY COMPLICATIONS IN SURGICAL INTERVENTIONS ON PERIODONT IN PATIENTS WITH TYPE 2 DIABETES MELLITUS.

Authors

  • Gudaryan A. A. SE «Dnipropetrovsk medical academy Ministry of Health of Ukraine», Dnipro,Ukraine
  • Pertseva N. O. SE «Dnipropetrovsk medical academy Ministry of Health of Ukraine», Dnipro,Ukraine
  • Shandyba S. I. SE «Dnipropetrovsk medical academy Ministry of Health of Ukraine», Dnipro,Ukraine
  • Shirinkin S. V. SE «Dnipropetrovsk medical academy Ministry of Health of Ukraine», Dnipro,Ukraine
  • Cherednik D. A. SE «Dnipropetrovsk medical academy Ministry of Health of Ukraine», Dnipro,Ukraine

DOI:

https://doi.org/10.21856/j-PEP.2019.4.04

Keywords:

generalized periodontitis, diabetes mellitus type 2, flap operations, directed regeneration of bone tissue, HELBO-therapy

Abstract

Surgical treatment of generalized periodontitis in patients with type 2 diabetes mellitus, presents considerable difficulties associated with high-risk inflammatory complications caused lower local immunity and periodontitis infection. The purpose of this study is an improvement of methods of treatment and prevention of postoperative complications at the stage of regeneration of periodontal tissues in patients with generalized periodontitis and type 2 diabetes mellitus. Materials and methods. The article presents the results of the treatment and prevention of inflammatory complications during surgery in 64 patients with generalized periodontitis I-II severity with type 2 diabetes mellitus. Results. It was revealed that the risk of inflammatory complications after surgery directly depends on the presence of periodontal tissues of pathogenic bacteria, reduction of barrier function of the oral mucosa and cytokine imbalance in the system. Developed a program for tracking surgical operation of directed regeneration of periodontal tissues, consisting in antibacterial and immunocorrective therapy in combination with a local impact on the pathological focus by system HELBO. The use of individual components of the proposed treatment and diagnostic complex has been carried out before by both Ukrainian researchers and foreign authors. But such a complex effect on the main etiological factors and pathogenetic mechanisms of generalized periodontitis on the background of type 2 diabetes has not been applied to date. Conclusions. The proposed complex of therapeutic and preventive measures provides rapid relief of inflammatory complications in the early and late postoperative period, potentiates a full recovery of the defects of bone structures in patients with generalized periodontitis with type 2 diabetes mellitus.

References

Harsas NA, Lessang R, Soeroso Y, Putri GA. J Int Dental Med Res. 2019; 12(1): 175-180.

Preshaw PM. Int Dent J. 2010; 59(54): 5-11.

Duarte PM, et al. J Periodontol. 2012; 4: 426-434. doi:http://doi.org/10.1902/jop.2011.110324.

Graves DT, Kayal RA. Front Biosci. 2008; 13: 1227. doi:http://doi.org/10.2741/2757.

Marsh PD. J Clin Periodontol. 2005; 32(6): 7-15. doi: http://doi.org/10.1111/j.1600-051X.2005.00790.x

Hujoel P, Zina L, Cunha-Cruz J, Lopez R. Eur J Oral Sci. 2013; 121: 2-6. doi: http://doi.org/ 10.1111/eos.12011.

Rescala B, Rosalem WJ, Teles RP, et al. J Periodontol.2010; 81: 1308-1316. doi: http://doi.org/10.1902/jop.2010.090643.

Degasperi GR, et al. Adv Microbiol. 2018; 8(01): 1-17. doi: http://doi.org/10.4236/aim.2018.81001.

King GL. J Periodontol. 2008; 79(8): 1527-1534. doi:http://doi.org/10.1902/jop.2008.080246.

Tunes RS, Foss-Freitas MC. J Can Dent Assoc. 2010; 76(35): 1-7.

Knight ET, et al. Periodontology. 2016; 71(1): 22-51. doi:http://doi.org/10.1111/prd.12110.

Haseeb M, Khawaja KI, Ataullah K, et al. J Coll Physicians Surg Pak. 2012; 22(8): 514-518. doi:http://doi.org/ 08.2012/JCPSP.514518.

Andersen R, Loebel N, Hammond D, Wilson M. J Clin Dent 2007; 18(2): 1-5.

Georgios ER, Brink B. J General Dentistry 2010: 68-73.

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Published

2019-11-11

How to Cite

Gudaryan, A. A., Pertseva, N. O., Shandyba, S. I., Shirinkin, S. V., & Cherednik, D. A. (2019). PREVENTION AND COMPLEX TREATMENT OF INFLAMMATORY COMPLICATIONS IN SURGICAL INTERVENTIONS ON PERIODONT IN PATIENTS WITH TYPE 2 DIABETES MELLITUS. Problems of Endocrine Pathology, 70(4), 28-37. https://doi.org/10.21856/j-PEP.2019.4.04

Issue

Section

CLINICAL ENDOCRINOLOGY