THE CLINICAL AND FUNCTIONAL STATE OF THE THYROID GLAND IN CHILDREN FROM ECOLOGICALLY UNFAVOURABLE AREAS IN THE DYNAMICS OF TREATMENT
Keywords:thyroid gland, clinical state, thyroid gland hormones, ecopathology, treatment, children
During the period from 2015 to 2017, 359 children between the ages of three and sixteen who originated from and still live in the ecologically unfavourable areas (EUA) of Ivano-Frankivsk region were examined by clinical, laboratory and instrumental means.The aim of the research is to prove the effectiveness of adequate therapy for thyroid ecodependent diseases treatment. The method of the research involves the general clinical and ultrasonic testing of the thyroid gland,as well as the study of its T3 and T4 hormones activity since the pa 3 and T4 hormones activity since the pathology of the thyroid gland is the leading pathology among other ecop T4 thology of the thyroid gland is the leading pathology among other ecopathologies in children from ecologically unfavourable areas. The incidence of almost all analyzed complaints in children from the ecologically unfavour able areas has been higher than in children from ecologically favourable areas. Among the most frequent com plaints from both groups were as follows: emotional lability and excitement (64 % – 72 %),especially in children from the EUAs, headaches (up to 58 %), appetite disorders (49 % – 56 %), fatigability (21 % – 45 %), tachycardia (up to 18 %),and hyperhidrosis (up to 9 %), i.e.complaints common for goitre and unspecific general intoxication. The level of T3 and T4 thyroid hormones revealed that subclinical hypothyroidism is common in areas af 3 and T4 thyroid hormones revealed that subclinical hypothyroidism is common in areas affected by radiation T4 fected by radiation pollution and endemic goitre, whereas subclinical hyperthyroidism is common in chemically polluted areas. The study results demonstrate the effectiveness of the therapy by means of membrane protectors, entero sorbents and iodine preparations, which brought back the indexes of clinical and functional state of the thyroid gland to almost normal in the studied children.
Antypkin JuG. Mystectvo Likuvannja 2005; 2: 16-23.
Pearce HS, Brabant G, Duntas LH. Eur Thyroid J 2013; 2(4): 215-228. https://doi.org/10.1159/000356507 .
Buldygina JuV. Klinichna Endokrynologija ta Endokrynna Hirurgija 2009; 4: 9-14.
Sokolova SS, Sergijenko LJu, Gjevorkjan AR, et al. Probl Endokryn Patologii’ 2017; 1: 45-54. https://doi.org/10.21856/UJRN/j-PEP.2017.4.8 .
Chernjavskaja IV, Romanova IP, Dorosh EG. Probl Endokryn Patologii’ 2017; 2: 49-57.
Mamenko MJe. Pediatrija, Akusherstvo ta Ginekologija 2011; 3: 49-52.
Lytvynec’ LJa, Synovers’ka OS. Bukovyns’kyj Med Visn 2012; 1: 177.
Matveeva SL, Gojdenko NI, Jurchenko SL. Probl Endokryn Patologii’ 2015; 3: 67-71.
Mamenko MJe. Zdorov’e Rebenka 2008; 3(12): 32-36.
Gajdajev JuO. Ukr Med Chasopys 2007; 5: 3-8.
Vadzjuk SN, Jurchyshyn OM. Visn Nauk Doslidzh 2011; 2: 19-21.
Majdannik VG, Burlaj VG, Gnatejko OZ, et al. Propedevticheskaja pediatrija, Vinnica, 2017: 888 p.